Exome Sequencing Identifies Compound Heterozygous Mutations inSCN5AAssociated with Congenital Complete Heart Block in the Thai Population
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چکیده
منابع مشابه
Exome Sequencing Identifies Compound Heterozygous Mutations in SCN5A Associated with Congenital Complete Heart Block in the Thai Population
Background. Congenital heart block is characterized by blockage of electrical impulses from the atrioventricular node (AV node) to the ventricles. This blockage can be caused by ion channel impairment that is the result of genetic variation. This study aimed to investigate the possible causative variants in a Thai family with complete heart block by using whole exome sequencing. Methods. Genomi...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2016
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2016/3684965